Insulin not only moves glucose into the cells, but it also escorts Vitamin C. Blood sugar hogs the seats on the bus in most diabetics, therefore reducing the amount of Vitamin C we can absorb. This is the premise of The GAA Theory: high glucose levels hinder vitamin C entry into cells.

Vitamin C is vitally important for many functions throughout the body - a big one being metabolism. Glucose and Vitamin C are similar in the way they enter the cells. Both molecules require help from insulin. The name for the process that brings glucose and Vitamin C through cell membranes is insulin-mediated uptake. The insulin-mediated uptake of glucose and vitamin C uses white blood cells. White blood cells have more insulin pumps and they may contain 20 times the amount of vitamin C as ordinary cells.

So does increasing your Vitamin C help boost your glycemic control? Diabetes Health cited a study that confirms daily doses of 2,000 mg of absorbic acid improved both fasting blood glucose and HbA1c readings in patients with type 2 diabetes. Next time you swing by the store - see if some Emergen-C can help you achieve better glycemic control. With 1,000 mg of Vitamin C per packet - their homepage says: Feel The Good. Little did they know how good it could be for Type 2 diabetics!

Ed Hinerman, a life insurance specialist with the Hinerman Group, was posed an interesting challenge recently. For years he has successfully found affordable life insurance for many adults with type 1 diabetes, but he had never been asked about life insurance for children with Type 1 diabetes until now.

After speaking with underwriters in the top 40 or so companies, he found a discernible lack of interest due to lack of data. Companies would say that they couldn't consider someone with type 1 diabetes until they were either age 15 or age 20. A peer in the industry told Ed the knee jerk reaction was because insurance companies haven't done mortality studies on children. They simply don't have any data upon which to base the pricing for products. Uh oh!! That coupled with the fact that there really isn't any financial incentive for them to study and create products for a relatively small market that would produce relatively low premium, kind of sets the tone. Well, now the war has been defined and the battles are becoming clearer.

When Ed contacted the ADA for assistance in this matter - hold your breath (it's a shocker!) - they turned a cold shoulder on a diabetic's need. What if the diabetic's parents were doing what so many families do - and trying to buy a whole life policy to help pay for their kids college someday? It's really not fair! Here's where fair begins -- Ed asked me to gather some facts it will take to get the insurance companies attention. Does anybody have any idea of the mortality rate of children after being diagnosed with type 1 diabetes?

Bottom line. Life insurance companies make big money and for them to cut and run from children just because it might not make them more big bucks, or because they really haven't done their homework and aren't interested in doing it, isn't acceptable. Game on! I hope we can make a good showing, at the very least - hit one out of the park for the fans. Thanks for inviting me to play, Ed!

Creator of Diabetes Health Magazine, Scott King, has been a type 1 diabetic for over 34 years. Needless to say, he knows diabetes, and he is doing a remarkable job of introducing cutting-edge treatments for diabetics. In the first Diabetes Health TV broadcast, he shared interviews from the recent AADE Conference. A really exciting product he featured is called Neuragen - a topical treatment for diabetes neuropathy.

With diabetes neuropathy, people experience pain due to damage to the peripheral nerves. Neuropathic pain is often characterized by burning sensations or shooting pain, or may occur as numbness or chronic itching. Clinical trials have shown Neuragen to be effective in 70% of patients for the pain associated with diabetes. The ingredients are pretty kosher, too. Neuragen is made of a proprietary blend of essential oils from special species of geranium, lavender, bergamot, eucalyptus, and tea tree.

The Neuragen rep was blunt when he described the effective nature of this all natural product - using more does not make it any more effective! You have to admire his refreshing honesty. But like I said upfront - if Scott King is willing to spend the time getting the scoop on this product - it's probably worth your time using it. For more interviews, checkot the full coverage of the AADE Conference on Diabetes Health TV!

Nutrigenetics is the study of the interaction of genes and diet. The Diet Channel has published an article explaining what nutrigenetics is and how it will revolutionize the world of diabetes.

Researchers believe elevated blood sugar can be mapped back to a genetic reaction. Drugs are only overriding the cause of elevated blood sugar and forcing the sugar into the cells, causing damage over time. Nutrigenetics is addressing the cause of the elevated blood sugar and may suggest a better diet to control your diabetes. Genes control how you metabolize certain vitamins, minerals, and nutrients. These genes can vary from one individual to the next. See what happens to Buddy the Elf when he consumes way too much coffee? Yes, I know - that's Hollywood. Nevertheless - a comical example of what nutrigenetics explores.

Consumer-friendly tests are available for these gene and diet interactions. The tests are done with a cheek swab. You send your swab off to a specialized lab, which analyzes DNA from the cheek cells. You receive a report identifying your gene variations. A qualified health professional can explain the test results, and make specific diet and supplement recommendations to optimize your health. If this is a test you're interested in taking, Sciona's Mycellf Program will be happy to prepare your profile. Open up and say Ahhhh.

Yesterday I posted on the latest indicator that high fructose corn syrup is harmful and maybe even linked to diabetes risk. Naturally, the American Beverage Association vigorously rejects the report.

In the interest of balance, here's the opposing argument courtesy of the ABA's website. "There is absolutely no unique link between soft drinks sweetened with high fructose corn syrup (HFCS) and diabetes, in children or adults. In fact, it is a stretch of the imagination to link the laboratory findings of this unpublished in vitro study with the occurrence of diabetes in humans." Ooh, "unpublished." Ouch. Nice veiled barb, there.

The statement goes on in some detail, basically saying if the harmful reactive carbonyls occur naturally in a number of foods, why single out HFCS?

Well, you can't blame them for defending themselves. But I laughed at the following: "Singling out any one food, beverage or ingredient as a unique cause or contributor to diabetes is simply not supported by science." I dunno. A study led by a professor of food science at Rutgers. Sure sounds like science to me...

Ever heard of MedCo Health Solutions? It's not a household name like the big pharmaceutical companies Novo, Glaxo etc. However, MedCo, which happens to be in the prescription benefit management business, is a large and powerful company. Now it's about to become even larger: the company is poised to pay $1.5 billion for PolyMedica Corporation, the nation's biggest supplier of diabetes-related products.

According to a Forbes report on the deal, PolyMedica has nearly one million patients using its products. Its product line includes Liberty Healthcare brand, blood glucose test kits and meters, lancet kits, insulin and the like. The Forbes article says the move is basically a smart one on the part of MedCo: it can cash in on the growing demand(14.5 % growth, annually!) for diabetes supplies. MedCo's chief exec, David Snow, told Forbes he anticipates the purchase could make his company (indirectly) the supplier of diabetes treatment products to half of all insured Americans with diabetes.

Factoid: ads for PolyMedica star "Cocoon" and "Seinfeld" actor Wilford Brimley.

What's small, green and cute? Nah, not Kermit the Frog. It's the Renew Lancing System. I was just checking out Amy T's review of this and other cool/interesting new diabetes-related gadgetry on her site, Diabetes Mine.

The Renew Advanced Lancing System: it's sleek, small, and in cool colors - retro lime green and silver. But the name! "Renew Advanced Lancing System" - jeepers, couldn't they have thought of something a little catchier?? Anyway, it's a handy little self-contained, disposable lancing unit that contains twenty needles. Don't bother checking out the website, 'cause there's no info on there yet. Hmm...

Amy gives the thumbs-down to another newie: the DUO-CARE, a combined blood glucose and blood pressure monitor. The idea is okay, but the design: ugh. It takes the form of a huge and clunky wrist bracelet. Remember how guys in the 80s wore those enormous, square digital watches. It looks like that - times twenty! Interesting idea, but a loser, design-wise. (Mind you, if people will use the Exubera mega-inhaler, who's to say they won't buy this, too?)

We applaud Amy's view that diabetes gadgets need to lose the hospital-bed-pan-look. Keep searching for the coolest new stuff, Amy! And here's hoping your terrific letter makes it into the hands of Steve Jobs.

A lot of people I know avoid foods that list high fructose corn syrup (HFCS) as an ingredient. Apart from the calories they add to foods, there's a growing belief that lab-devised products like HFCS are simply unnatural and may be harmful. Wikipedia has an interesting article on the origins and controversy surrounding HFCS, if you want to learn more.

Not surprisingly, the food industry has always defended HFCS against claims that it is harmful. But here's the latest contradiction of that claim: a recent study found that HFCS is "astonishingly" high in reactive carbonyls, which are thought to contribute to the development of diabetes. The study was led by Dr. Chi-tang Ho, head of Rutgers University's Department of Food Science, and colleagues. They concluded that one can of HFCS-sweetened soda contains five times the reactive carbonyls that are normally found in the blood of a person with diabetes.

A news release by the American Chemical Society, announcing Dr. Ho's findings, notes that previous studies have already linked HFCS to cell and tissue damage. They suggest that HFCS consumption may raise the risk of diabetes, not to mention obesity. Say's Dr. Ho: "People consume too much high-fructose corn syrup in this country. It's in way too many food and drink products and there's growing evidence that it's bad for you."

Drug War '07: drug giants Novo Nordisk and Sanofi-Aventis have been sparring recently over their insulin pen designs. Novo alleges Sanofi has stolen its design ideas, basically. Check out Bev's post on this to learn more.

The reason it's such a big deal to them is money. The insulin pen could be super-lucrative for investors. Meanwhile, here's some news that's bound to get big pharma even more excited: a new study reports that insulin pens are cheaper and more effective than insulin shots.

Why so good? Fewer trips to the emergency room and fewer visits to the doctor. Insulin pens boast a pre-measured dosing system, with each dose of insulin contained in a single, disposable cartridge. This eliminates the risk of over- or under-dosing, says senior author of the study, Dr. Rajesh Balkrishnan of Ohio State University in Columbus. The researchers say that study participants who used an insulin pen instead of a regular syringe ended up reducing their annual healthcare costs by nearly $17,000. Wow.

What I'm not clear on here is whether or not they factored in the added expense of upgrading from syringes to insulin pens.

Want to know more? The study has been published in the latest issue of Clinical Therapeutics, but you can click here to read a summary.

Medical gadget manufacturer Medtronic has teamed up with LifeScan, maker of blood glucose meters. The powers-that-be at those companies say they want to introduce a fab new blood glucose meter to the US market. The meters will be developed by LifeScan for Medtronic and should be reasonably high-tech, with wireless transmission of test results to Medtronic's MiniMed Paradigm pumps or the Guardian REAL-Time continuous monitoring system. Tying it all together: Medtronic's CareLink diabetes management software. The plan is to get the meters on the market by early 2008.

The press release announcing the deal made me laugh. It stresses that, in addition to their alliance, Medtronic and LifeScan "will also educate people about the importance of insulin pump therapy and proactive diabetes management." Oh, ha ha. Translation: "buy our stuff. Please!" It's okay Medtronic and LifeScan. Just be yourselves. You exist to make money. We understand that. Just be honest about it and spare us the whole "education" angle.

Oramed is developing a soft gel insulin capsule for the treatment of diabetes. The company has recently announced it the successful completion of its clinical trial demonstrating the safety and efficacy of the oral insulin gel capsule.

The pills were shown to reduce blood sugar, with no significant adverse effects. The insulin used in the gel caps is a generic brand of human insulin. The duration of the insulin is similar to Regular. But the most beautiful thing about these gel caps is that they reintroduce the liver into glucose metabolism, thereby reducing the likelihood of dangerous lows associated with injected insulin and oral medications. This could blow away the necessity of blood sugar testing because you are regulating glucose metabolism in the liver, like a person without diabetes.

Up until now, the idea of insulin pills or tablets was inconceivable due to the fact that insulin, when swallowed, breaks down in the digestive system. Oramed's patented technology overcame the problem of digestion as well as permeability to the intestine. The company's goal is for the completion of formal Phase 1 studies in the US by mid-2008. Sign me up!

It's free, it covers 70% of the Earth's surface, and it's a remedy for all living things. So why do physicians rarely promote the curative properties of water?

Every plant needs it to survive. Every living thing on Earth requires water - even the cacti of the Sahara Desert. We are no different. Mike Adams, of News Target, was one of the last people to interview the late Dr. Batmanghelidj. The things he learned about "The Healing Power of Water" left him in awe. The conversation revealed which ailments and "diseases" are actually caused by dehydration, why the general population is chronically dehydrated and henceforth labeled diseased, what ingredients deplete the body's water reserves, why thirst is not a reliable indicator of dehydration, the dynamics of cholesterol and how water keeps it in balance, how dehydration impairs mental functioning and potentially causes depression, in addition to recognizing signs that your body is starting to dehydrate.

It's a world of answers to an often overlooked question. The premise of the interview is this one thing: the human body manifests dehydration by producing pain, and pain is a sign of water shortage in the body, and water shortage is actually the background to most of the health problems in our society. If the aforementioned interests you in the least - I strongly encourage you to follow the river of curiosity to its source. Who knows? Maybe we're all dying of thirst.

Remember the big food poisoning disaster involving Peter Pan peanut butter? That was back in February. Well, one of the victims was Atlanta resident Linda Moore (59), who has diabetes. Moore told the Atlanta Journal-Constitution that she always kept a jar of Peter Pan on her bedside table in case she needed a quick blood sugar lift. She never dreamed it could make her so sick.

What's awful about Moore's story is that she ate the tainted peanut butter and became ill after the recall had been issued. Several weeks after, in fact. She says she was just so busy with her job as a nurse that she had not had time to catch up on the news. One morning Moore ate some Peter Pan then left for work. She soon fell violently ill and ended up being hospitalized for three days with salmonella poisoning. The AJC does not say how Moore's experience was affected by her having diabetes. She is now suing ConAgra, Peter Pan's parent company.

Meanwhile, the Atlanta Journal-Constitution is also running a story about Peter Pan and how the brand is struggling to make a comeback after the deadly food poisoning mishap. Needless to say, Linda Moore says she will never again buy that brand. In fact, she may never eat peanut butter again. "When I'm in the grocery store, I just look and keep moving," she told the AJC.

Ever had food poisoning? I have. I felt like I was dying. Childbirth was easier. I am not kidding.

The results are looking good for the first-round of human testing for Oral-lyn, Generex's flagship product. The oral insulin, delivered into the body through the oral cavity (with no deposit in the lungs), is as effective as injected insulin.

The efficacy of Oral-lyn for controlling blood sugar was decidedly as good as multiple insulin injections. The research found that regular insulin and Generex Oral-lyn had similar effects on lowering blood sugar in subjects with type 1 diabetes. The subjects received twice-daily insulin analogue for basal coverage. So this might rewind some of us old timers to the days long-gone where we could get by with two shots. Period. If Oral-lyn makes it to the local pharmacies - maybe mealtime corrections could be easy to swallow. Praise patient compliance!

On an even more impressive note - it looks like the mucosal membrane in the lungs is giving Exubera negative challenges to overcome. Perhaps Oral-lyn will come out looking a little more pristine in this capacity, since it doesn't go anywhere near the lung membranes. I'm not in favor of diabusiness - but for crying out loud - I'd like to see some companies start working for their money. Generex is one of those companies with the Big Idea!

Pfizer's bandwagon might be busted! Turns-out a study says inhaled human insulin, whether formulated as a powder or liquid, is more immunogenic than injected insulin.

Adverse effects of antibody formation have not been thoroughly investigated. But it was shown, comparatively, that inhaled insulin provokes more of an immune response than injections. Spitting is a dirty habit - but it's not good for nothing. The mucosal defense system is the body's primary line of defense against inhaled foreign matter - kind of like the MARINES of the human body. It is uniquely able to discern self from non-self bodies. So far - it looks like Pfizer's toker is a no go.

As I said before - the adverse events have not been thoroughly investigated. Until we know exactly what kind of mucosal revenge or pulmonary punishment lies ahead - I'd stick to the tried and true...subQ, for now. However the Generex Oral-lyn human trials are looking pretty promising. Stay tuned.